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GLP-1 Therapy

Understanding GLP-1 & GIP Medications

Semaglutide and tirzepatide, explained clearly so you know exactly what you're taking and why.

Semaglutide

A GLP-1 Medication

Semaglutide activates GLP-1, a hormone your gut naturally releases after eating.  Semaglutide gives that signal in a stronger, more consistent dose. 
Slows Digestion

Food stays in your stomach longer, so you feel full sooner and longer. 

Quiets Food Noise

Reduces the constant thoughts about food,  many people call "food noise".

Tirzepatide

A GLP-1 and GIP Medication

Tirzepatide activates GLP-1, the same hormone semaglutide targets -  AND GIP, a second gut hormone that appears to strengthen GLP-1 effect on appetite and blood sugar when the two work together.
Improves Insulin Response

Helps your body manage blood sugar more efficiently. 

Slows Digestion

Food stays in your stomach longer, so you feel full sooner and longer. 

Quiets Food Noise

The added GIP effect often means a stronger reduction in appetite for many patients. 

Improves Insulin Response

GLP-1 and GIP working together improve blood sugar management beyond either hormone alone. 

CHOOSING BETWEEN THEM
SEMAGLUTIDE OR TIRZEPATIDE?
BOTH ARE EFFECTIVE, WELL-STUDIED OPTIONS. HERE'S HOW THEY COMPARE. 

SEMAGLUTIDE

Longer real-world track record

Generally lower cost

Well-tolerated starting point for most patients

Dual-hormone approach targets more than one appetite pathway

Often associated with greater average weight loss in studies

TIRZEPATIDE

WHAT TO EXPECT

 Side Effects

Both medication have the same side effects.  They are most common early on or after a dose increase:
Nausea
Constipation
Bloating
Fatigue
These typically ease as your body adjusts, starting low and titrating slowly is how we keep it manageable.  
SOURCING
Compounded vs. Brand-Name
Brand-name GLP-1 (Ozempic®, Wegovy®, Mounjaro®, Zepbound®) are made and sold by the original manufacturer.  Compounded semaglutide and tirzepatide are prepared by a licensed compounding pharmacy instead - here's how they compare.
Same Active Ingredient
Compounded semaglutide and tirzepatide use the same active ingredient as brand-name Ozempic®, Wegovy®, Mounjaro®, and Zepbound®. Because it isn't prepared by the original manufacturer, it's considered a non-FDA-approved medication — made instead by a licensed compounding pharmacy under state and, where applicable, federal oversight. We work only with licensed, reputable pharmacies to ensure quality and safety.
What's Different
Brand-name products come in pre-filled, fixed-dose pens. Compounded versions are typically dispensed as a vial, allowing more flexible, provider-guided dosing — often at a lower cost.
PRICING
Compounded semaglutide and tirzepatide are each available three ways,  so you can choose what fits your routine. Pricing adjusts as your dose increases.  You'll know your exact cost at every step before you move forward. 
Semaglutide

In-Office Weekly Injections - starting at $40/weekly

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Take-Home Weekly Injections - starting at $145/month

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Take-Home Vials - starting at $180 shipping included

Tirzepatide

In-Office Weekly Injections - starting at $50/weekly

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Take-Home Weekly Injections - starting at $185/month

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Take-Home Vials - starting at $230 shipping included

ReNew
Weight
Loss &
Wellness
Johnson City, TN
Where your wellness journey truly begins.
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© 2026 ReNew Weight Loss & Wellness. All rights reserved.

The information on this website is for general informational purposes only and does not constitute medical advice, diagnosis, or treatment.  All treatment decisions are made by a licensed medical provider based on individual patient evaluation.  Individual results vary.  ReNew Weight Loss & Wellness is located in Johnson City, TN and operates in compliance with Tennessee state healthcare regulations. 

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